| Gene Information | |
|---|---|
| Gene Name | SNX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 450 |
| Protein Names | Sorting nexin-4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000114520 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O95219 |
| Gene Card | SNX4 |
| Uniprot ID | O95219 |
| Pfam | PF00787 |
| In ASD | no |
| Allosteric Prediction | no (-0.454337434) |
| Ortholog in Animals | Alpaca_ SNX4 ( ortholog_one2one ) Dog_ SNX4 ( ortholog_one2one ) GuineaPig_ SNX4 ( ortholog_one2one ) Macaque_ SNX4 ( ortholog_one2one ) Mouse_ Snx4 ( ortholog_one2one ) Pig_ SNX4 ( ortholog_one2one ) Rat_ Snx4 ( ortholog_one2one ) Rabbit_ SNX4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNX5, SNX6, SNX2, SNX18, SNX7, SNX33, SNX10, SNX1, SNX11, SNX12, SNX3, SNX30, SNX8, SNX32, SNX9 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome membrane {ECO:0000269|PubMed:17994011, ECO:0000269|PubMed:32513819, ECO:0000269|PubMed:33468622}; Peripheral membrane protein {ECO:0000269|PubMed:17994011}; Cytoplasmic side {ECO:0000269|PubMed:17994011}. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC). {ECO:0000269|PubMed:17994011}. |
| Mouse PG classification | NA |
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