| Gene Information | |
|---|---|
| Gene Name | MOATB |
| Organism | Homo sapiens (Human) |
| Gene Length | 1325 |
| Protein Names | ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15439 |
| Gene Card | ABCC4 |
| Uniprot ID | O15439 |
| Pfam | PF00664; PF00005 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. sinusoidal membrane of hepatocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11568681 rs11568689 rs4148460 rs45454092 rs11568658 rs11568684 rs2274407 rs11568701 rs11568705 rs11568668 rs11568669 rs753414892 rs11568699 rs11568697 rs9282570 rs3765534 rs146708960 rs11568659 rs11568694 rs45477596 rs139970608 rs45504892 rs11568644 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:11106685, ECO:0000269|PubMed:12883481, ECO:0000269|PubMed:26721430}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:11856762, ECO:0000269|PubMed:26721430}; Multi-pass membrane protein {ECO:0000255}. Note=Its localization to the basolateral or apical membranes is tissue-dependent. {ECO:0000305|PubMed:26721430}. |
| Mouse PG classification | NA |
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