| Gene Information | |
|---|---|
| Gene Name | SNTG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 517 |
| Protein Names | Gamma-1-syntrophin (G1SYN) (Syntrophin-4) (SYN4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000147481 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NSN8 |
| Gene Card | SNTG1 |
| Uniprot ID | Q9NSN8 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.381828739) |
| Ortholog in Animals | Alpaca_ SNTG1 ( ortholog_one2one ) Dog_ SNTG1 ( ortholog_one2one ) GuineaPig_ SNTG1 ( ortholog_one2one ) Macaque_ SNTG1 ( ortholog_one2one ) Mouse_ Sntg1 ( ortholog_one2one ) Pig_ SNTG1 ( ortholog_one2one ) Rat_ Sntg1 ( ortholog_one2one ) Rabbit_ SNTG1 ( ortholog_one2one ) |
| Ohnologs | SNTG2 |
| Paralogs | SNTG2, SNTB1, SNTA1, SNTB2 |
| Tissue | NA |
| Tissue Specificity | Brain specific. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. No expression in muscle cells. {ECO:0000269|PubMed:10747910}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7PC7 (X-ray 2.10A ) 7PC8 (X-ray 2.50A ) 7QQN (X-ray 2.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Nucleus. Note=Mainly cytoplasmic and weakly nuclear. |
| Mouse PG classification | NA |
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