| Gene Information | |
|---|---|
| Gene Name | SLC6A13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 602 |
| Protein Names | Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) |
| Target Name | sodium- and chloride-dependent gaba transporter 2 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000010379 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NSD5 |
| Gene Card | SLC6A13 |
| Uniprot ID | Q9NSD5 |
| Pfam | PF00209 |
| In ASD | no |
| Allosteric Prediction | no (-0.876362205) |
| Ortholog in Animals | Alpaca_ SLC6A13 ( ortholog_one2one ) Dog_ SLC6A13 ( ortholog_one2one ) GuineaPig_ SLC6A13 ( ortholog_one2one ) Mouse_ Slc6a13 ( ortholog_one2one ) Pig_ SLC6A13 ( ortholog_one2one ) Rat_ Slc6a13 ( ortholog_one2one ) |
| Ohnologs | SLC6A6, SLC6A11 |
| Paralogs | SLC6A20, SLC6A9, SLC6A2, SLC6A18, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A5, SLC6A14, SLC6A6, SLC6A15, SLC6A11, SLC6A19, SLC6A1, SLC6A17, SLC6A12, SLC6A3 |
| Tissue | kidney, liver |
| Tissue Specificity | Expressed in brain, kidney, lung, liver and testis. {ECO:0000269|PubMed:11824941, ECO:0000269|PubMed:17502375}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs577294 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22932902}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000250|UniProtKB:P31649}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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