| Gene Information | |
|---|---|
| Gene Name | SLC6A17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197106 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H1V8 |
| Gene Card | SLC6A17 |
| Uniprot ID | Q9H1V8 |
| Pfam | PF00209 |
| In ASD | no |
| Allosteric Prediction | no (-0.788680112) |
| Ortholog in Animals | Alpaca_ SLC6A17 ( ortholog_one2one ) Dog_ SLC6A17 ( ortholog_one2one ) GuineaPig_ SLC6A17 ( ortholog_one2one ) Macaque_ SLC6A17 ( ortholog_one2one ) Mouse_ Slc6a17 ( ortholog_one2one ) Pig_ SLC6A17 ( ortholog_one2one ) Rat_ Slc6a17 ( ortholog_one2one ) Rabbit_ SLC6A17 ( ortholog_one2one ) |
| Ohnologs | SLC6A15 |
| Paralogs | SLC6A20, SLC6A9, SLC6A2, SLC6A18, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A5, SLC6A14, SLC6A6, SLC6A15, SLC6A13, SLC6A11, SLC6A19, SLC6A1, SLC6A12, SLC6A3 |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum, hypothalamus, pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12737742 rs775085213 rs375380880 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P31662}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P31662}. Postsynapse {ECO:0000250|UniProtKB:Q8BJI1}. Presynapse {ECO:0000250|UniProtKB:Q8BJI1}. Note=Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals. {ECO:0000250|UniProtKB:Q8BJI1}. |
| Mouse PG classification | NA |
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