| Gene Information | |
|---|---|
| Gene Name | TRIP12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1992 |
| Protein Names | E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000153827 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14669 |
| Gene Card | TRIP12 |
| Uniprot ID | Q14669 |
| Pfam | PF00632 |
| In ASD | no |
| Allosteric Prediction | no (-0.925255246) |
| Ortholog in Animals | Alpaca_ TRIP12 ( ortholog_one2one ) Dog_ TRIP12 ( ortholog_one2one ) GuineaPig_ TRIP12 ( ortholog_one2one ) Macaque_ TRIP12 ( ortholog_one2one ) Mouse_ Trip12 ( ortholog_one2one ) Pig_ TRIP12 ( ortholog_one2one ) Rat_ Trip12 ( ortholog_one2one ) Rabbit_ TRIP12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HERC4, NEDD4, HECTD1, NEDD4L, UBE3B, HUWE1, SMURF1, AREL1, UBR5, HERC2, HECW2, HERC3, WWP1, UBE3A, UBE3C, SMURF2, HACE1, HECTD2, HECTD4, ITCH, HECW1, WWP2, HERC5, HERC6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1300458163 rs373429636 rs1553602821 rs866079762 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:20208519}. |
| Mouse PG classification | NA |
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