| Gene Information | |
|---|---|
| Gene Name | ABHD6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | Monoacylglycerol lipase ABHD6 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 6) |
| Target Name | monoacylglycerol lipase abhd6 |
| Target Type | Patented-recorded target |
| Gene Age | 680 ( ENSG00000163686 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BV23 |
| Gene Card | ABHD6 |
| Uniprot ID | Q9BV23 |
| Pfam | PF00561 |
| In ASD | no |
| Allosteric Prediction | yes (0.062313841) |
| Ortholog in Animals | Alpaca_ ABHD6 ( ortholog_one2one ) Dog_ ABHD6 ( ortholog_one2one ) GuineaPig_ ABHD6 ( ortholog_one2one ) Macaque_ ABHD6 ( ortholog_one2one ) Mouse_ Abhd6 ( ortholog_one2one ) Pig_ ABHD6 ( ortholog_one2one ) Rat_ Abhd6 ( ortholog_one2one ) Rabbit_ ABHD6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERHL2, MEST, EPHX4, ABHD8, ABHD11, EPHX2, ABHD5, ABHD4, ABHD14B, BPHL, ABHD14A, EPHX3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OTS (X-ray 1.79A ) |
| DBSNP | rs200333190 rs11544004 rs199678322 rs199696239 rs745824058 |
| Subcellular location [CC] | Late endosome membrane {ECO:0000250|UniProtKB:Q8R2Y0}; Single-pass type II membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000250|UniProtKB:Q8R2Y0}; Single-pass type II membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q8R2Y0}; Single-pass type II membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |