| Gene Information | |
|---|---|
| Gene Name | SLC36A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 476 |
| Protein Names | Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (hPAT1) (Solute carrier family 36 member 1) |
| Target Name | proton-coupled amino acid transporter 1 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000123643 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z2H8 |
| Gene Card | SLC36A1 |
| Uniprot ID | Q7Z2H8 |
| Pfam | PF01490 |
| In ASD | no |
| Allosteric Prediction | yes (0.103925411) |
| Ortholog in Animals | Alpaca_ SLC36A1 ( ortholog_one2one ) Dog_ SLC36A1 ( ortholog_one2one ) GuineaPig_ SLC36A1 ( ortholog_one2one ) Macaque_ SLC36A1 ( ortholog_one2one ) Mouse_ Slc36a1 ( ortholog_one2one ) Pig_ SLC36A1 ( ortholog_one2one ) Rat_ Slc36a1 ( ortholog_one2one ) Rabbit_ SLC36A1 ( ortholog_one2one ) |
| Ohnologs | SLC36A4 |
| Paralogs | SLC38A3, SLC36A4, SLC38A10, SLC38A9, SLC36A3, SLC38A7, SLC38A8, SLC38A2, SLC36A2, SLC38A4, SLC38A11, SLC38A6, SLC32A1, SLC38A1, SLC38A5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9687945 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12527723, ECO:0000269|PubMed:12809675, ECO:0000269|PubMed:19549785}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:12527723}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:17897319}; Multi-pass membrane protein {ECO:0000255}. Note=In neurons, colocalizes with the exocyst complex in the axonal processes. {ECO:0000250|UniProtKB:Q924A5}. |
| Mouse PG classification | NA |
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