| Gene Information | |
|---|---|
| Gene Name | PGLYRP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha) |
| Target Name | peptidoglycan recognition protein 3 |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000159527 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96LB9 |
| Gene Card | PGLYRP3 |
| Uniprot ID | Q96LB9 |
| Pfam | PF01510 |
| In ASD | no |
| Allosteric Prediction | no (-0.763333174) |
| Ortholog in Animals | Alpaca_ PGLYRP3 ( ortholog_one2one ) GuineaPig_ PGLYRP3 ( ortholog_one2one ) Macaque_ PGLYRP3 ( ortholog_one2one ) Mouse_ Pglyrp3 ( ortholog_one2one ) Pig_ PGLYRP3 ( ortholog_one2one ) Rat_ Pglyrp3b ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PGLYRP1, PGLYRP4, PGLYRP2 |
| Tissue | esophagus, skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin, vagina |
| Tissue Specificity | Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain. {ECO:0000269|PubMed:11461926, ECO:0000269|PubMed:16354652}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1SK3 (X-ray 2.80A ) 1SK4 (X-ray 1.65A ) 1TWQ (X-ray 2.30A ) 2APH (X-ray 2.10A ) |
| DBSNP | rs55991125 rs843971 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:16354652}. |
| Mouse PG classification | NA |
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