Gene Information
Gene NameGUCY1B2
OrganismHomo sapiens (Human)
Gene Length617
Protein NamesGuanylate cyclase soluble subunit beta-2 (GCS-beta-2) (EC 4.6.1.2)
Target Nameguanylate cyclase
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO75343
Gene CardGUCY1B2
Uniprot IDO75343
PfamPF00211; PF07700; PF07701
In ASDno
Allosteric Predictionyes (0.043601722)
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in gastric signet ring cell carcinoma, but not in the normal stomach. {ECO:0000269|PubMed:10777682}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs9568497  rs11841997  rs1328361 
Subcellular location [CC]Cytoplasm.
Mouse PG classificationNA
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