| Gene Information | |
|---|---|
| Gene Name | PRKCH |
| Organism | Homo sapiens (Human) |
| Gene Length | 683 |
| Protein Names | Protein kinase C eta type (EC 2.7.11.13) (PKC-L) (nPKC-eta) |
| Target Name | pkc-eta messenger rna |
| Target Type | Literature-reported target |
| Gene Age | 987 ( ENSG00000027075 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P24723 |
| Gene Card | PRKCH |
| Uniprot ID | P24723 |
| Pfam | PF00130; PF00168; PF00069; PF00433 |
| In ASD | no |
| Allosteric Prediction | yes (0.977336201) |
| Ortholog in Animals | Alpaca_ PRKCH ( ortholog_one2one ) Dog_ PRKCH ( ortholog_one2one ) GuineaPig_ PRKCH ( ortholog_one2one ) Macaque_ PRKCH ( ortholog_one2one ) Mouse_ Prkch ( ortholog_one2one ) Pig_ PRKCH ( ortholog_one2one ) Rat_ Prkch ( ortholog_one2one ) Rabbit_ PRKCH ( ortholog_one2one ) |
| Ohnologs | PRKCE |
| Paralogs | PKN3, PKN1, PRKCE, PRKCZ, PRKCI, PKN2, PRKCG, PRKCA, PRKCB |
| Tissue | NA |
| Tissue Specificity | Most abundant in lung, less in heart and skin. {ECO:0000269|PubMed:1986216}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FK9 (X-ray 1.75A ) 3TXO (X-ray 2.05A ) |
| DBSNP | rs55645551 rs55737090 rs55848048 rs55818778 rs2230500 rs11846991 rs1378993559 rs34159231 rs35561533 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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