| Gene Information | |
|---|---|
| Gene Name | SNX30 |
| Organism | Homo sapiens (Human) |
| Gene Length | 574 |
| Protein Names | Sorting nexin-33 (SH3 and PX domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000148158 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8WV41 |
| Gene Card | SNX33 |
| Uniprot ID | Q8WV41 |
| Pfam | PF10456; PF00787; PF14604 |
| In ASD | no |
| Allosteric Prediction | no (-1.664773057) |
| Ortholog in Animals | Alpaca_ SNX30 ( ortholog_one2one ) Dog_ SNX30 ( ortholog_one2one ) GuineaPig_ SNX30 ( ortholog_one2one ) Macaque_ SNX30 ( ortholog_one2one ) Mouse_ Snx30 ( ortholog_one2one ) Pig_ SNX30 ( ortholog_one2one ) Rat_ Snx30 ( ortholog_one2one ) Rabbit_ SNX30 ( ortholog_one2one ) |
| Ohnologs | SNX7 |
| Paralogs | SNX5, SNX6, SNX2, SNX18, SNX7, SNX33, SNX10, SNX4, SNX1, SNX11, SNX12, SNX3, SNX8, SNX32, SNX9 |
| Tissue | NA |
| Tissue Specificity | Detected in heart and pancreas. {ECO:0000269|PubMed:18353773}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4AKV (X-ray 2.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:21048941}. |
| Mouse PG classification | NA |
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