| Gene Information | |
|---|---|
| Gene Name | SLC44A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 706 |
| Protein Names | Choline transporter-like protein 2 (Solute carrier family 44 member 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000129353 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IWA5 |
| Gene Card | SLC44A2 |
| Uniprot ID | Q8IWA5 |
| Pfam | PF04515 |
| In ASD | no |
| Allosteric Prediction | yes (0.318868592) |
| Ortholog in Animals | Alpaca_ SLC44A2 ( ortholog_one2one ) Dog_ SLC44A2 ( ortholog_one2one ) GuineaPig_ SLC44A2 ( ortholog_one2one ) Macaque_ SLC44A2 ( ortholog_one2one ) Mouse_ Slc44a2 ( ortholog_one2one ) Pig_ SLC44A2 ( ortholog_one2one ) Rat_ Slc44a2 ( ortholog_one2one ) Rabbit_ SLC44A2 ( ortholog_one2one ) |
| Ohnologs | SLC44A5, SLC44A4 |
| Paralogs | SLC44A4, SLC44A1, SLC44A5, SLC44A3 |
| Tissue | NA |
| Tissue Specificity | Present in supporting cells of the inner ear (at protein level). Only isoform 3 is expressed in inner ear vestibular tissue. {ECO:0000269|PubMed:14973250, ECO:0000269|PubMed:20665236}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2288904 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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