| Gene Information | |
|---|---|
| Gene Name | SLC19A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Thiamine transporter 2 (ThTr-2) (ThTr2) (Solute carrier family 19 member 3) |
| Target Name | solute carrier family 19 member 3 |
| Target Type | Literature-reported target |
| Gene Age | 987 ( ENSG00000135917 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BZV2 |
| Gene Card | SLC19A3 |
| Uniprot ID | Q9BZV2 |
| Pfam | PF01770 |
| In ASD | no |
| Allosteric Prediction | no (-1.000351114) |
| Ortholog in Animals | Alpaca_ SLC19A3 ( ortholog_one2one ) Dog_ SLC19A3 ( ortholog_one2one ) GuineaPig_ SLC19A3 ( ortholog_one2one ) Macaque_ SLC19A3 ( ortholog_one2one ) Mouse_ Slc19a3 ( ortholog_one2one ) Pig_ SLC19A3 ( ortholog_one2one ) Rat_ Slc19a3 ( ortholog_one2one ) Rabbit_ SLC19A3 ( ortholog_one2one ) |
| Ohnologs | SLC19A1, SLC19A2 |
| Paralogs | SLC19A2, SLC19A1 |
| Tissue | adipose.tissue, greater.omentum, subcutaneous.adipose.tissue |
| Tissue Specificity | Widely expressed but most abundant in placenta, kidney and liver. {ECO:0000269|PubMed:11136550, ECO:0000269|PubMed:15871139}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121917882 rs59736804 rs34507036 rs121917884 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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