Gene Information
Gene NameSF3A3
OrganismHomo sapiens (Human)
Gene Length501
Protein NamesSplicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61)
Target Namesplicing factor 3a subunit 3
Target TypeNA
Gene Age>4290 ( ENSG00000183431 )
Evolutionary StageEukaryota
AlphaFoldDBQ12874
Gene CardSF3A3
Uniprot IDQ12874
PfamPF16837; PF12108; PF11931
In ASDno
Allosteric Predictionno (-0.635198109)
Ortholog in AnimalsAlpaca_ SF3A3 ( ortholog_one2one )
Dog_ SF3A3 ( ortholog_one2many )
GuineaPig_ SF3A3 ( ortholog_one2one )
Macaque_ SF3A3 ( ortholog_one2one )
Mouse_ Sf3a3 ( ortholog_one2one )
Pig_ SF3A3 ( ortholog_one2one )
Rat_ Sf3a3 ( ortholog_one2one )
Rabbit_ SF3A3 ( ortholog_one2one )
OhnologsNA
ParalogsSDE2
TissueNA
Tissue SpecificityUbiquitous.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.197137(Rat);0.145627(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2DT7  (NMR  -  )  5Z56  (EM  5.10A  )  5Z57  (EM  6.50A  )  5Z58  (EM  4.90A  )  6AH0  (EM  5.70A  )  6AHD  (EM  3.80A  )  6FF7  (EM  4.50A  )  6QX9  (EM  3.28A  )  6Y50  (EM  4.10A  )  6Y53  (EM  7.10A  )  6Y5Q  (EM  7.10A  )  7ABG  (EM  7.80A  )  7ABH  (EM  4.50A  )  7ABI  (EM  8.00A  )  7EVO  (EM  2.50A  )  7ONB  (EM  3.10A  )  7Q3L  (EM  2.30A  )  7Q4O  (EM  2.20A  )  7Q4P  (EM  2.20A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus speckle {ECO:0000269|PubMed:8022796}. Nucleus {ECO:0000269|PubMed:10882114, ECO:0000269|PubMed:21349847, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:30315277}.
Mouse PG classificationNA
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