| Gene Information | |
|---|---|
| Gene Name | SNX21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 373 |
| Protein Names | Sorting nexin-21 (Sorting nexin L) (SNX-L) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000124104 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q969T3 |
| Gene Card | SNX21 |
| Uniprot ID | Q969T3 |
| Pfam | PF00787 |
| In ASD | no |
| Allosteric Prediction | no (-1.15871756) |
| Ortholog in Animals | Alpaca_ SNX21 ( ortholog_one2one ) Dog_ SNX21 ( ortholog_one2one ) GuineaPig_ SNX21 ( ortholog_one2one ) Macaque_ SNX21 ( ortholog_one2one ) Mouse_ Snx21 ( ortholog_one2one ) Pig_ SNX21 ( ortholog_one2one ) Rat_ Snx21 ( ortholog_one2one ) Rabbit_ SNX21 ( ortholog_one2one ) |
| Ohnologs | SNX20 |
| Paralogs | SNX20 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in fetus liver, but only weakly expressed in brain, skeleton muscle, smooth muscle, and cardiac muscle, kidney, and adrenal gland. {ECO:0000269|PubMed:12459172}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4638862 |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q3UR97}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Early endosome membrane {ECO:0000250|UniProtKB:Q3UR97}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q3UR97}; Cytoplasmic side {ECO:0000250|UniProtKB:Q3UR97}. |
| Mouse PG classification | NA |
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