| Gene Information | |
|---|---|
| Gene Name | PPH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1038 |
| Protein Names | Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13873 |
| Gene Card | BMPR2 |
| Uniprot ID | Q13873 |
| Pfam | PF01064; PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HLQ (X-ray 1.45A ) 3G2F (X-ray 2.35A ) 6UNP (X-ray 2.30A ) 7PPA (X-ray 1.48A ) 7PPB (X-ray 2.40A ) 7PPC (X-ray 3.60A ) 7U5O (X-ray 3.45A ) |
| DBSNP | rs1085307172 rs1085307177 rs1085307185 rs1085307197 rs1085307215 rs137852743 rs137852750 rs137852750 rs137852754 rs754343081 rs767882551 rs137852744 rs1085307324 rs1085307354 rs137852745 rs137852749 rs137852746 rs1085307364 rs1085307365 rs2228545 rs1006246556 rs137852752 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:25187962}; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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