| Gene Information | |
|---|---|
| Gene Name | SND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 910 |
| Protein Names | Staphylococcal nuclease domain-containing protein 1 (EC 3.1.31.1) (100 kDa coactivator) (EBNA2 coactivator p100) (Tudor domain-containing protein 11) (p100 co-activator) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000197157 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7KZF4 |
| Gene Card | SND1 |
| Uniprot ID | Q7KZF4 |
| Pfam | PF00565; PF00567 |
| In ASD | no |
| Allosteric Prediction | yes (0.259727344) |
| Ortholog in Animals | Alpaca_ SND1 ( ortholog_one2one ) Dog_ SND1 ( ortholog_one2one ) GuineaPig_ SND1 ( ortholog_one2one ) Macaque_ SND1 ( ortholog_one2one ) Mouse_ Snd1 ( ortholog_one2one ) Pig_ SND1 ( ortholog_one2one ) Rat_ Snd1 ( ortholog_one2one ) Rabbit_ SND1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | STK31 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:7651391}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E6N (NMR - ) 2HQE (X-ray 2.00A ) 2HQX (X-ray 1.42A ) 2O4X (X-ray 2.00A ) 3BDL (X-ray 1.90A ) 3OMC (X-ray 1.77A ) 3OMG (X-ray 1.85A ) 4QMG (X-ray 2.70A ) 5M9O (X-ray 1.45A ) 7KNW (X-ray 2.65A ) 7KNX (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14508492, ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:12234934, ECO:0000269|PubMed:14508492, ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:7651391}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000269|PubMed:12234934, ECO:0000269|PubMed:17081065}. |
| Mouse PG classification | NA |
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