| Gene Information | |
|---|---|
| Gene Name | SNCG |
| Organism | Homo sapiens (Human) |
| Gene Length | 127 |
| Protein Names | Gamma-synuclein (Breast cancer-specific gene 1 protein) (Persyn) (Synoretin) (SR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000173267 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O76070 |
| Gene Card | SNCG |
| Uniprot ID | O76070 |
| Pfam | PF01387 |
| In ASD | no |
| Allosteric Prediction | no (-0.391680908) |
| Ortholog in Animals | Alpaca_ SNCG ( ortholog_one2one ) Dog_ SNCG ( ortholog_one2one ) GuineaPig_ SNCG ( ortholog_one2one ) Macaque_ SNCG ( ortholog_one2one ) Mouse_ Sncg ( ortholog_one2one ) Pig_ SNCG ( ortholog_one2one ) Rat_ Sncg ( ortholog_one2one ) Rabbit_ SNCG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNCA, SNCB |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9864 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11746666}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11746666}. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle. |
| Mouse PG classification | NA |
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