| Gene Information | |
|---|---|
| Gene Name | KCTD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 257 |
| Protein Names | BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000134504 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q719H9 |
| Gene Card | KCTD1 |
| Uniprot ID | Q719H9 |
| Pfam | PF02214 |
| In ASD | no |
| Allosteric Prediction | no (-1.036559258) |
| Ortholog in Animals | Alpaca_ KCTD1 ( ortholog_one2one ) Dog_ KCTD1 ( ortholog_one2one ) Macaque_ KCTD1 ( ortholog_one2one ) Mouse_ Kctd1 ( ortholog_one2one ) Pig_ KCTD1 ( ortholog_one2one ) Rat_ Kctd1 ( ortholog_one2one ) |
| Ohnologs | KCTD15, KCTD6, KCTD4, KCTD21 |
| Paralogs | KCTD16, KCTD21, KCTD7, KCNRG, KCTD8, KCTD15, KCTD14, KCTD12, KCTD18, KCTD4, KCTD6, KCTD11, KCTD19 |
| Tissue | NA |
| Tissue Specificity | Expressed in mammary gland, kidney, brain and ovary. {ECO:0000269|PubMed:18358072}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5BXB (X-ray 2.17A ) 5BXD (X-ray 1.80A ) 6S4L (X-ray 2.42A ) |
| DBSNP | rs587776998 rs587776999 rs587776999 rs587777001 rs587777000 rs587777003 rs587777002 rs491684 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18358072}. |
| Mouse PG classification | NA |
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