| Gene Information | |
|---|---|
| Gene Name | SNAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 547 |
| Protein Names | Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q969I6 |
| Gene Card | SLC38A4 |
| Uniprot ID | Q969I6 |
| Pfam | PF01490 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed almost exclusively in embryonic and adult liver, and at lower levels in the kidney (PubMed:11342143, PubMed:11414754). Expressed at lower levels in adult muscle and pancreas (PubMed:11414754). Detected in fetal blood vessels (PubMed:16148032). Expressed in syncytiotrophoblas of placenta during first trimester and at term (PubMed:19015196, PubMed:16148032). Highly expressed in first trimester placenta compared to term placenta (PubMed:19015196). {ECO:0000269|PubMed:11342143, ECO:0000269|PubMed:11414754, ECO:0000269|PubMed:16148032, ECO:0000269|PubMed:19015196}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2429467 rs11183610 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11414754, ECO:0000269|PubMed:16148032}; Multi-pass membrane protein {ECO:0000269|PubMed:11414754}. Cell projection, microvillus membrane {ECO:0000269|PubMed:19015196}; Multi-pass membrane protein. Note=Microvillus membrane localization in placenta. {ECO:0000269|PubMed:19015196}. |
| Mouse PG classification | NA |
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