| Gene Information | |
|---|---|
| Gene Name | SET1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1707 |
| Protein Names | Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15047 |
| Gene Card | SETD1A |
| Uniprot ID | O15047 |
| Pfam | PF11764; PF00076; PF00856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3S8S (X-ray 1.30A ) 3UVN (X-ray 1.79A ) 4EWR (X-ray 1.50A ) |
| DBSNP | rs897985 rs781482552 rs772206552 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:17355966}. Chromosome {ECO:0000269|PubMed:17355966}. Note=Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes. |
| Mouse PG classification | NA |
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