| Gene Information | |
|---|---|
| Gene Name | SNAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 206 |
| Protein Names | Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P60880 |
| Gene Card | SNAP25 |
| Uniprot ID | P60880 |
| Pfam | PF00835 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.181828(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KIL (X-ray 2.30A ) 1XTG (X-ray 2.10A ) 2N1T (NMR - ) 3DDA (X-ray 1.50A ) 3DDB (X-ray 1.60A ) 3RK2 (X-ray 2.20A ) 3RK3 (X-ray 3.50A ) 3RL0 (X-ray 3.80A ) 3ZUR (X-ray 2.71A ) 5W7I (X-ray 2.10A ) 5W7J (X-ray 2.20A ) 6JLH (X-ray 2.37A ) |
| DBSNP | rs1555794286 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P60879}. Cell membrane {ECO:0000250|UniProtKB:P60881}; Lipid-anchor {ECO:0000250|UniProtKB:P60879}. Synapse, synaptosome {ECO:0000250|UniProtKB:P60879}. Photoreceptor inner segment {ECO:0000250|UniProtKB:P60879}. Note=Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). Colocalizes with PLCL1 at the cell membrane (By similarity). {ECO:0000250|UniProtKB:P60879, ECO:0000250|UniProtKB:P60881}. |
| Mouse PG classification | NA |
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