| Gene Information | |
|---|---|
| Gene Name | ZPBP |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Zona pellucida-binding protein 1 (Inner acrosomal membrane IAM38) (Sp38) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000042813 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BS86 |
| Gene Card | ZPBP |
| Uniprot ID | Q9BS86 |
| Pfam | PF07354 |
| In ASD | no |
| Allosteric Prediction | no (-1.302515808) |
| Ortholog in Animals | Alpaca_ ZPBP ( ortholog_one2one ) Dog_ ZPBP ( ortholog_one2one ) Macaque_ ZPBP ( ortholog_one2one ) Mouse_ Zpbp ( ortholog_one2one ) Pig_ ZPBP ( ortholog_one2one ) Rat_ Zpbp ( ortholog_one2one ) Rabbit_ ZPBP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZPBP2 |
| Tissue | testis |
| Tissue Specificity | Expressed specifically in testis. {ECO:0000269|PubMed:17664285}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs202231065 rs61696422 rs1299521157 rs1468321681 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:31985809}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:Q62522}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q62522}. Secreted {ECO:0000305}. Note=First localized in acrosome granule, later migrates to the inner and outer acrosomal membrane. Released after the acrosomal reaction. {ECO:0000250|UniProtKB:Q62522}. |
| Mouse PG classification | NA |
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