| Gene Information | |
|---|---|
| Gene Name | SMYD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 490 |
| Protein Names | Histone-lysine N-methyltransferase SMYD1 (EC 2.1.1.354) (SET and MYND domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000115593 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NB12 |
| Gene Card | SMYD1 |
| Uniprot ID | Q8NB12 |
| Pfam | PF00856; PF01753 |
| In ASD | no |
| Allosteric Prediction | no (-1.27200804) |
| Ortholog in Animals | Alpaca_ SMYD1 ( ortholog_one2one ) Dog_ SMYD1 ( ortholog_one2one ) GuineaPig_ SMYD1 ( ortholog_one2one ) Macaque_ SMYD1 ( ortholog_one2one ) Mouse_ Smyd1 ( ortholog_one2one ) Pig_ SMYD1 ( ortholog_one2one ) Rat_ Smyd1 ( ortholog_one2one ) Rabbit_ SMYD1 ( ortholog_one2one ) |
| Ohnologs | SMYD2, SMYD3 |
| Paralogs | SMYD2, SMYD4, SMYD5, SMYD3, ZMYND15 |
| Tissue | heart, skeletal.muscle, artery, left.atrium, left.ventricle, mitral.valve, penis, pulmonary.valve, tongue |
| Tissue Specificity | Expression seems mostly restricted to heart and skeletal muscle. {ECO:0000269|PubMed:19783823}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1542087 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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