| Gene Information | |
|---|---|
| Gene Name | SLC10A6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Sodium-dependent organic anion transporter (SOAT) (Solute carrier family 10 member 6) (SLC10A6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000145283 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q3KNW5 |
| Gene Card | SLC10A6 |
| Uniprot ID | Q3KNW5 |
| Pfam | PF01758 |
| In ASD | no |
| Allosteric Prediction | no (-0.467481419) |
| Ortholog in Animals | Alpaca_ SLC10A6 ( ortholog_one2one ) Dog_ SLC10A6 ( ortholog_one2one ) GuineaPig_ SLC10A6 ( ortholog_one2one ) Macaque_ SLC10A6 ( ortholog_one2one ) Mouse_ Slc10a6 ( ortholog_one2one ) Pig_ SLC10A6 ( ortholog_one2one ) Rat_ Slc10a6 ( ortholog_one2one ) Rabbit_ SLC10A6 ( ortholog_one2one ) |
| Ohnologs | SLC10A2 |
| Paralogs | SLC10A2, SLC10A4, SLC10A1, SLC10A3, SLC10A5 |
| Tissue | esophagus, skin |
| Tissue Specificity | Highly expressed in testis, placenta and pancreas. Moderately expressed in heart, lung and mammary gland. Weakly expressed in brain, colon, kidney, liver, ovary, prostate, small intestine, spleen and thymus. {ECO:0000269|PubMed:17491011, ECO:0000269|PubMed:23667501}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17694522 rs13106574 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:23667501}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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