| Gene Information | |
|---|---|
| Gene Name | FBXL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 621 |
| Protein Names | F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000112234 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UKA2 |
| Gene Card | FBXL4 |
| Uniprot ID | Q9UKA2 |
| Pfam | PF00646 |
| In ASD | no |
| Allosteric Prediction | no (-0.70460032) |
| Ortholog in Animals | Alpaca_ FBXL4 ( ortholog_one2one ) Dog_ FBXL4 ( ortholog_one2one ) GuineaPig_ FBXL4 ( ortholog_one2one ) Macaque_ FBXL4 ( ortholog_one2one ) Mouse_ Fbxl4 ( ortholog_one2one ) Pig_ FBXL4 ( ortholog_one2one ) Rat_ Fbxl4 ( ortholog_one2one ) Rabbit_ FBXL4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXL22, FBXL3, FBXL13, FBXL17, FBXL16, FBXL19, FBXL5, FBXL18, FBXL14, FBXL2, FBXL20, FBXL6, FBXL15, SKP2, FBXL7 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle. {ECO:0000269|PubMed:10531037}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1350566881 rs772037717 rs398123061 rs1554215979 rs398123062 rs398123060 rs201989042 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Mitochondrion. |
| Mouse PG classification | NA |
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