| Gene Information | |
|---|---|
| Gene Name | SMOC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 434 |
| Protein Names | SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000198732 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H4F8 |
| Gene Card | SMOC1 |
| Uniprot ID | Q9H4F8 |
| Pfam | PF07648; PF10591; PF00086 |
| In ASD | no |
| Allosteric Prediction | no (-1.427406851) |
| Ortholog in Animals | Alpaca_ SMOC1 ( ortholog_one2one ) Dog_ SMOC1 ( ortholog_one2one ) GuineaPig_ SMOC1 ( ortholog_one2one ) Macaque_ SMOC1 ( ortholog_one2one ) Mouse_ Smoc1 ( ortholog_one2one ) Pig_ SMOC1 ( ortholog_one2one ) Rat_ Smoc1 ( ortholog_one2one ) Rabbit_ SMOC1 ( ortholog_one2one ) |
| Ohnologs | SMOC2 |
| Paralogs | SMOC2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen. {ECO:0000269|PubMed:12130637}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10150925 rs776638586 rs1365818420 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:12130637, ECO:0000269|PubMed:20359165}. Note=In or around the basement membrane. |
| Mouse PG classification | HPG |
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