| Gene Information | |
|---|---|
| Gene Name | SNRK |
| Organism | Homo sapiens (Human) |
| Gene Length | 765 |
| Protein Names | SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase) |
| Target Name | snf-related serine/threonine-protein kinase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163788 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NRH2 |
| Gene Card | SNRK |
| Uniprot ID | Q9NRH2 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.135483367) |
| Ortholog in Animals | Alpaca_ SNRK ( ortholog_one2one ) Dog_ SNRK ( ortholog_one2one ) GuineaPig_ SNRK ( ortholog_one2one ) Macaque_ SNRK ( ortholog_one2one ) Mouse_ Snrk ( ortholog_one2one ) Pig_ SNRK ( ortholog_one2one ) Rat_ Snrk ( ortholog_one2one ) Rabbit_ SNRK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TSSK6, SIK2, SIK3, NIM1K, NUAK2, TSSK2, TSSK4, SIK1, PRKAA2, BRSK2, NUAK1, BRSK1, HUNK, PRKAA1, TSSK1B, MELK, TSSK3 |
| Tissue | NA |
| Tissue Specificity | Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis. {ECO:0000269|PubMed:12234663, ECO:0000269|PubMed:8654423}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5YKS (X-ray 2.90A ) |
| DBSNP | rs35624204 rs56104180 rs368877591 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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