| Gene Information | |
|---|---|
| Gene Name | SMNDC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 238 |
| Protein Names | Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000119953 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75940 |
| Gene Card | SMNDC1 |
| Uniprot ID | O75940 |
| Pfam | PF06003 |
| In ASD | no |
| Allosteric Prediction | no (-0.679886125) |
| Ortholog in Animals | Alpaca_ SMNDC1 ( ortholog_one2one ) Dog_ SMNDC1 ( ortholog_one2one ) GuineaPig_ SMNDC1 ( ortholog_one2one ) Macaque_ SMNDC1 ( ortholog_one2one ) Mouse_ Smndc1 ( ortholog_one2one ) Pig_ SMNDC1 ( ortholog_one2one ) Rat_ Smndc1 ( ortholog_one2one ) Rabbit_ SMNDC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SMN1, SMN2 |
| Tissue | NA |
| Tissue Specificity | Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas. {ECO:0000269|PubMed:9817934}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.042424(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4A4F (NMR - ) 4A4H (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:11331295, ECO:0000269|PubMed:9817934}. Nucleus, Cajal body {ECO:0000269|PubMed:11331295}. Note=Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. {ECO:0000269|PubMed:11331295}. |
| Mouse PG classification | NA |
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