| Gene Information | |
|---|---|
| Gene Name | GRIN3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1115 |
| Protein Names | Glutamate receptor ionotropic, NMDA 3A (GluN3A) (N-methyl-D-aspartate receptor subtype 3A) (NMDAR3A) (NR3A) (NMDAR-L) |
| Target Name | nmda receptor |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000198785 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TCU5 |
| Gene Card | GRIN3A |
| Uniprot ID | Q8TCU5 |
| Pfam | PF00060; PF10613 |
| In ASD | yes |
| Allosteric Prediction | yes (1.258689925) |
| Ortholog in Animals | Alpaca_ GRIN3A ( ortholog_one2one ) Dog_ GRIN3A ( ortholog_one2one ) GuineaPig_ GRIN3A ( ortholog_one2one ) Macaque_ GRIN3A ( ortholog_one2one ) Mouse_ Grin3a ( ortholog_one2one ) Pig_ GRIN3A ( ortholog_one2one ) Rat_ Grin3a ( ortholog_one2one ) Rabbit_ GRIN3A ( ortholog_one2one ) |
| Ohnologs | GRIN2D, GRIN3B, GRIN1 |
| Paralogs | GRIN2A, GRIK5, GRIN2C, GRID1, GRID2, GRIK3, GRIN2D, GRIN1, GRIK4, GRIA3, GRIK1, GRIA2, GRIA1, GRIN3B, GRIK2, GRIA4, GRIN2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs558734093 rs111415222 rs773593066 rs10989591 rs144427058 rs776062103 rs34755188 rs10989589 rs773322226 rs371244839 rs142284927 rs1360008284 rs144770241 rs10989563 rs144712629 rs141253502 rs755464674 rs3739722 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9R1M7}; Multi-pass membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}. Postsynaptic density {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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