| Gene Information | |
|---|---|
| Gene Name | SLC6A6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 620 |
| Protein Names | Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000131389 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P31641 |
| Gene Card | SLC6A6 |
| Uniprot ID | P31641 |
| Pfam | PF00209 |
| In ASD | no |
| Allosteric Prediction | no (-0.594682659) |
| Ortholog in Animals | Alpaca_ SLC6A6 ( ortholog_one2one ) Dog_ SLC6A6 ( ortholog_one2one ) GuineaPig_ SLC6A6 ( ortholog_one2one ) Macaque_ SLC6A6 ( ortholog_one2one ) Mouse_ Slc6a6 ( ortholog_one2one ) Pig_ SLC6A6 ( ortholog_one2one ) Rat_ Slc6a6 ( ortholog_one2one ) Rabbit_ SLC6A6 ( ortholog_one2one ) |
| Ohnologs | SLC6A13, SLC6A12 |
| Paralogs | SLC6A20, SLC6A9, SLC6A2, SLC6A18, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A5, SLC6A14, SLC6A15, SLC6A13, SLC6A11, SLC6A19, SLC6A1, SLC6A17, SLC6A12, SLC6A3 |
| Tissue | NA |
| Tissue Specificity | Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. {ECO:0000269|PubMed:8010975, ECO:0000269|PubMed:8382624}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1042350 rs1042351 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:31345061, ECO:0000269|PubMed:31903486}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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