| Gene Information | |
|---|---|
| Gene Name | CDC45 |
| Organism | Homo sapiens (Human) |
| Gene Length | 566 |
| Protein Names | Cell division control protein 45 homolog (PORC-PI-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000093009 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75419 |
| Gene Card | CDC45 |
| Uniprot ID | O75419 |
| Pfam | PF02724 |
| In ASD | no |
| Allosteric Prediction | no (-0.087019055) |
| Ortholog in Animals | Alpaca_ CDC45 ( ortholog_one2one ) Dog_ CDC45 ( ortholog_one2one ) GuineaPig_ CDC45 ( ortholog_one2one ) Macaque_ CDC45 ( ortholog_one2one ) Mouse_ Cdc45 ( ortholog_one2one ) Pig_ CDC45 ( ortholog_one2one ) Rat_ Cdc45 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, bone.marrow, colon, dura.mater, spleen, testis, tongue, brain |
| Tissue Specificity | Widely expressed, highest levels are found in adult testis and thymus and in fetal liver. |
| Pharmacological Animal Models | 0.095960(Chimpanzee);0.147094(Mouse);NULL(Rat);0.117014(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5DGO (X-ray 2.10A ) 6XTX (EM 3.29A ) 6XTY (EM 6.77A ) 7PFO (EM 3.20A ) 7PLO (EM 2.80A ) |
| DBSNP | rs879255633 rs879255632 rs13447203 rs9606030 rs540217942 rs754080445 rs151279621 rs146559223 rs17209274 rs13447263 rs751663397 rs1376596361 rs778665661 |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:35585232}. Chromosome {ECO:0000305|PubMed:35585232}. Note=Associates with chromatin. {ECO:0000305|PubMed:35585232}. |
| Mouse PG classification | NA |
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