| Gene Information | |
|---|---|
| Gene Name | CCS |
| Organism | Homo sapiens (Human) |
| Gene Length | 274 |
| Protein Names | Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) |
| Target Name | copper chaperone for superoxide dismutase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000173992 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14618 |
| Gene Card | CCS |
| Uniprot ID | O14618 |
| Pfam | PF00403; PF00080 |
| In ASD | no |
| Allosteric Prediction | no (-0.079373787) |
| Ortholog in Animals | Alpaca_ CCS ( ortholog_one2one ) Dog_ CCS ( ortholog_one2one ) GuineaPig_ CCS ( ortholog_one2one ) Macaque_ CCS ( ortholog_one2one ) Mouse_ Ccs ( ortholog_one2one ) Pig_ CCS ( ortholog_one2one ) Rat_ Ccs ( ortholog_one2one ) Rabbit_ CCS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SOD1, SOD3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DO5 (X-ray 2.75A ) 2CRL (NMR - ) 2RSQ (NMR - ) 6FN8 (X-ray 1.55A ) 6FOL (X-ray 2.55A ) 6FON (X-ray 3.05A ) 6FP6 (X-ray 3.00A ) |
| DBSNP | rs142340643 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9726962}. |
| Mouse PG classification | NA |
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