| Gene Information | |
|---|---|
| Gene Name | SERPINA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 415 |
| Protein Names | Thyroxine-binding globulin (Serpin A7) (T4-binding globulin) |
| Target Name | thyroxine-binding globulin |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000123561 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P05543 |
| Gene Card | SERPINA7 |
| Uniprot ID | P05543 |
| Pfam | PF00079 |
| In ASD | yes |
| Allosteric Prediction | yes (1.00024259) |
| Ortholog in Animals | Alpaca_ SERPINA7 ( ortholog_one2one ) Dog_ SERPINA7 ( ortholog_one2one ) GuineaPig_ SERPINA7 ( ortholog_one2one ) Macaque_ SERPINA7 ( ortholog_one2one ) Mouse_ Serpina7 ( ortholog_one2one ) Pig_ SERPINA7 ( ortholog_one2one ) Rat_ Serpina7 ( ortholog_one2one ) Rabbit_ SERPINA7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | liver |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CEO (X-ray 2.80A ) 2RIV (X-ray 1.50A ) 2RIW (X-ray 2.04A ) 2XN3 (X-ray 2.09A ) 2XN5 (X-ray 1.70A ) 2XN6 (X-ray 1.29A ) 2XN7 (X-ray 1.43A ) 4X30 (X-ray 1.55A ) 4YIA (X-ray 1.58A ) |
| DBSNP | rs72554662 rs28933689 rs28933688 rs1050086 rs2234036 rs28937312 rs1804495 rs72554659 rs72554658 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
| click here to return to the previous page | |