| Gene Information | |
|---|---|
| Gene Name | ATP6IP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 470 |
| Protein Names | V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15904 |
| Gene Card | ATP6AP1 |
| Uniprot ID | Q15904 |
| Pfam | PF20520; PF05827 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | widely expressed, with highest levels in brain and lowest in liver and duodenum. {ECO:0000269|PubMed:27231034}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.310265(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WLW (EM 3.00A ) 6WM2 (EM 3.10A ) 6WM3 (EM 3.40A ) 6WM4 (EM 3.60A ) 7U4T (EM 3.60A ) 7UNF (EM 4.08A ) |
| DBSNP | rs878853276 rs878853278 rs878853277 rs878853275 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:27231034}; Single-pass type I membrane protein {ECO:0000305}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:27231034}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O54715}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:O54715}; Single-pass type I membrane protein {ECO:0000305}. Note=Not detected in trans-Golgi network. {ECO:0000269|PubMed:27231034}. |
| Mouse PG classification | NA |
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