| Gene Information | |
|---|---|
| Gene Name | MYPT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 982 |
| Protein Names | Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60237 |
| Gene Card | PPP1R12B |
| Uniprot ID | O60237 |
| Pfam | PF12796; PF15898 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific. {ECO:0000269|PubMed:11067852, ECO:0000269|PubMed:9570949}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2843414 rs3881953 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12923170}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments. {ECO:0000269|PubMed:12923170}. |
| Mouse PG classification | NA |
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