| Gene Information | |
|---|---|
| Gene Name | TMEM65 |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Transmembrane protein 65 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000164983 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6PI78 |
| Gene Card | TMEM65 |
| Uniprot ID | Q6PI78 |
| Pfam | PF10507 |
| In ASD | no |
| Allosteric Prediction | no (-1.092744045) |
| Ortholog in Animals | Alpaca_ TMEM65 ( ortholog_one2one ) GuineaPig_ TMEM65 ( ortholog_one2one ) Macaque_ TMEM65 ( ortholog_one2one ) Mouse_ Tmem65 ( ortholog_one2one ) Pig_ TMEM65 ( ortholog_one2one ) Rat_ Tmem65 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed the ventricular tissue (at protein level). {ECO:0000269|PubMed:26403541}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17854113 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26403541}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion inner membrane {ECO:0000269|PubMed:24765583, ECO:0000269|PubMed:28295037}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes at the intercalated disk in the ventricular tissue (PubMed:26403541). {ECO:0000269|PubMed:26403541}. |
| Mouse PG classification | NA |
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