| Gene Information | |
|---|---|
| Gene Name | MMP11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 488 |
| Protein Names | Stromelysin-3 (SL-3) (ST3) (EC 3.4.24.-) (Matrix metalloproteinase-11) (MMP-11) |
| Target Name | stromelysin-3 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000099953 ) 3 ( ENSG00000275365 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P24347 |
| Gene Card | MMP11 |
| Uniprot ID | P24347 |
| Pfam | PF00045; PF00413 |
| In ASD | no |
| Allosteric Prediction | no (-0.474104769) |
| Ortholog in Animals | Alpaca_ MMP11 ( ortholog_one2one ) Dog_ MMP11 ( ortholog_one2one ) GuineaPig_ MMP11 ( ortholog_one2one ) Macaque_ MMP11 ( ortholog_one2one ) Mouse_ Mmp11 ( ortholog_one2one ) Pig_ MMP11 ( ortholog_one2one ) Rat_ Mmp11 ( ortholog_one2one ) Rabbit_ MMP11 ( ortholog_one2one ) |
| Ohnologs | MMP25, MMP2, MMP15, MMP8, MMP24, MMP7, MMP20, MMP27, MMP13, MMP3, MMP10, MMP1, MMP17 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP25, MMP28, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3 |
| Tissue | endometrium, placenta |
| Tissue Specificity | Specifically expressed in stromal cells of breast carcinomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs738792 rs28363646 rs28363647 rs28363648 rs17854940 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
| Mouse PG classification | NA |
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