| Gene Information | |
|---|---|
| Gene Name | NME8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 588 |
| Protein Names | Thioredoxin domain-containing protein 3 (NM23-H8) (NME/NM23 family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000086288 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8N427 |
| Gene Card | NME8 |
| Uniprot ID | Q8N427 |
| Pfam | PF00334; PF00085 |
| In ASD | no |
| Allosteric Prediction | no (-0.564890481) |
| Ortholog in Animals | Alpaca_ NME8 ( ortholog_one2one ) GuineaPig_ NME8 ( ortholog_one2one ) Macaque_ NME8 ( ortholog_one2one ) Mouse_ Nme8 ( ortholog_one2one ) Pig_ NME8 ( ortholog_one2one ) Rat_ Nme8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NME2, NME7, NME1, NME4, NME6, NME9, NME3, NME5 |
| Tissue | NA |
| Tissue Specificity | Testis-specific. Expressed only in primary spermatocytes and round spermatids. {ECO:0000269|PubMed:11737268}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2722372 rs10250905 rs56128139 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11737268}. |
| Mouse PG classification | NA |
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