Gene Information
Gene NamePYROXD2
OrganismHomo sapiens (Human)
Gene Length581
Protein NamesPyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (EC 1.-.-.-)
Target NameNA
Target TypeNA
Gene Age424 ( ENSG00000119943 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ8N2H3
Gene CardPYROXD2
Uniprot IDQ8N2H3
PfamPF01593
In ASDno
Allosteric Predictionno (-1.059830058)
Ortholog in AnimalsAlpaca_ PYROXD2 ( ortholog_one2one )
Dog_ PYROXD2 ( ortholog_one2one )
GuineaPig_ PYROXD2 ( ortholog_one2one )
Macaque_ PYROXD2 ( ortholog_one2one )
Mouse_ Pyroxd2 ( ortholog_one2one )
Pig_ PYROXD2 ( ortholog_one2one )
Rat_ Pyroxd2 ( ortholog_one2one )
Rabbit_ PYROXD2 ( ortholog_one2one )
OhnologsNA
ParalogsBLOC1S2, RETSAT
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17856170  rs2147896  rs2296441 
Subcellular location [CC]Mitochondrion matrix {ECO:0000269|PubMed:31170524}. Note=The import into mitochondria is dependent on TOMM40 and TIMM23. {ECO:0000269|PubMed:31170524}.
Mouse PG classificationNA
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