| Gene Information | |
|---|---|
| Gene Name | SLRR2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 352 |
| Protein Names | Keratocan (KTN) (Keratan sulfate proteoglycan keratocan) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60938 |
| Gene Card | KERA |
| Uniprot ID | O60938 |
| Pfam | PF13516; PF13855 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664). {ECO:0000269|PubMed:10802664, ECO:0000269|PubMed:11683372}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121917862 rs737111 rs121917858 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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