| Gene Information | |
|---|---|
| Gene Name | LGALS7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 136 |
| Protein Names | Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced gene 1 protein) |
| Target Name | galectin-7 |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000205076 ) 3 ( ENSG00000283082 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P47929 |
| Gene Card | LGALS7;LGALS7B |
| Uniprot ID | P47929 |
| Pfam | PF00337 |
| In ASD | no |
| Allosteric Prediction | no (-0.927952174) |
| Ortholog in Animals | Mouse_ Lgals7 ( ortholog_one2many ) Rat_ Lgals7 ( ortholog_one2many ) |
| Ohnologs | LGALS3 |
| Paralogs | LGALSL, GRIFIN, LGALS3, LGALS1, LGALS4, LGALS12, LGALS8, LGALS2, LGALS13, LGALS14, LGALS16, LGALS9B, LGALS9, LGALS9C, CLC, LGALS7B |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Mainly expressed in stratified squamous epithelium. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BKZ (X-ray 1.90A ) 2GAL (X-ray 2.00A ) 3GAL (X-ray 1.90A ) 3ZXE (X-ray 1.67A ) 3ZXF (X-ray 1.38A ) 4GAL (X-ray 1.95A ) 4UW3 (X-ray 1.48A ) 4UW4 (X-ray 1.77A ) 4UW5 (X-ray 2.04A ) 4UW6 (X-ray 1.79A ) 4XBQ (X-ray 2.23A ) 4Y26 (X-ray 2.61A ) 5GAL (X-ray 2.00A ) 5H9Q (X-ray 1.93A ) 5H9S (X-ray 1.82A ) 6VTO (X-ray 1.69A ) 6VTP (X-ray 2.30A ) 6VTQ (X-ray 1.95A ) 6VTR (X-ray 2.30A ) 6VTS (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11706006}. Nucleus {ECO:0000269|PubMed:11706006}. Secreted {ECO:0000305}. Note=May be secreted by a non-classical secretory pathway. |
| Mouse PG classification | NA |
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