Gene Information
Gene NameSF3B6
OrganismHomo sapiens (Human)
Gene Length125
Protein NamesSplicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000115128 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y3B4
Gene CardSF3B6
Uniprot IDQ9Y3B4
PfamPF00076
In ASDno
Allosteric Predictionno (-1.337693414)
Ortholog in AnimalsAlpaca_ SF3B6 ( ortholog_one2one )
Dog_ SF3B6 ( ortholog_one2one )
GuineaPig_ SF3B6 ( ortholog_one2one )
Macaque_ SF3B6 ( ortholog_one2one )
Mouse_ Sf3b6 ( ortholog_one2one )
Pig_ SF3B6 ( ortholog_one2one )
Rat_ Sf3b6 ( ortholog_one2one )
Rabbit_ SF3B6 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.011584(Rat);0.163163(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2F9D  (X-ray  2.50A  )  2F9J  (X-ray  3.00A  )  2FHO  (NMR  -  )  3LQV  (X-ray  2.38A  )  5Z56  (EM  5.10A  )  5Z57  (EM  6.50A  )  5Z58  (EM  4.90A  )  6AH0  (EM  5.70A  )  6AHD  (EM  3.80A  )  6FF4  (EM  16.00A  )  6FF7  (EM  4.50A  )  6Y53  (EM  7.10A  )  6Y5Q  (EM  7.10A  )  7ABG  (EM  7.80A  )  7ABH  (EM  4.50A  )  7ABI  (EM  8.00A  )  7DVQ  (EM  2.89A  )  7Q4O  (EM  2.20A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:27720643, ECO:0000269|PubMed:28541300}.
Mouse PG classificationNA
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