| Gene Information | |
|---|---|
| Gene Name | SERPINA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 427 |
| Protein Names | Kallistatin (Kallikrein inhibitor) (Peptidase inhibitor 4) (PI-4) (Serpin A4) |
| Target Name | kallistatin |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000100665 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P29622 |
| Gene Card | SERPINA4 |
| Uniprot ID | P29622 |
| Pfam | PF00079 |
| In ASD | no |
| Allosteric Prediction | yes (0.20221951) |
| Ortholog in Animals | Alpaca_ SERPINA4 ( ortholog_one2one ) Dog_ SERPINA4 ( ortholog_one2one ) Macaque_ SERPINA4 ( ortholog_one2one ) Pig_ SERPINA4 ( ortholog_one2one ) Rat_ Serpina4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | liver, gall.bladder, pancreas, kidney |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6F02 (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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