| Gene Information | |
|---|---|
| Gene Name | SLCO6A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 719 |
| Protein Names | Solute carrier organic anion transporter family member 6A1 (Cancer/testis antigen 48) (CT48) (Gonad-specific transporter) (GST) (Organic anion-transporting polypeptide 6A1) (Organic anion-transporting polypeptide I) (OATP-I) (Solute carrier family 21 member 19) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000205359 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q86UG4 |
| Gene Card | SLCO6A1 |
| Uniprot ID | Q86UG4 |
| Pfam | PF07648; PF03137 |
| In ASD | no |
| Allosteric Prediction | no (-0.621219525) |
| Ortholog in Animals | Alpaca_ SLCO6A1 ( ortholog_one2one ) Dog_ SLCO6A1 ( ortholog_one2one ) Macaque_ SLCO6A1 ( ortholog_one2one ) Mouse_ Slco6c1 ( ortholog_one2many ) Mouse_ Slco6d1 ( ortholog_one2many ) Pig_ SLCO6A1 ( ortholog_one2one ) Rat_ Slco6c1 ( ortholog_one2many ) Rat_ Slco6b1 ( ortholog_one2many ) Rat_ Slco6d1 ( ortholog_one2many ) Rabbit_ SLCO6A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLCO4C1, SLCO4A1, SLCO5A1, SLCO2B1, SLCO1B1, SLCO3A1, SLCO1B3, SLCO1C1, SLCO1A2, SLCO2A1 |
| Tissue | testis |
| Tissue Specificity | Strongly expressed in testis. Weakly expressed in spleen, brain, fetal brain and placenta. Detected in lung tumors. {ECO:0000269|PubMed:12677006, ECO:0000269|PubMed:15546177}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13190449 rs17150488 rs10073333 rs10055840 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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