Gene Information
Gene NameSTAMBP
OrganismHomo sapiens (Human)
Gene Length424
Protein NamesSTAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000124356 )
Evolutionary StageEukaryota
AlphaFoldDBO95630
Gene CardSTAMBP
Uniprot IDO95630
PfamPF01398; PF08969
In ASDno
Allosteric Predictionyes (0.13715657)
Ortholog in AnimalsAlpaca_ STAMBP ( ortholog_one2one )
Dog_ DGUOK ( ortholog_one2one )
GuineaPig_ STAMBP ( ortholog_one2one )
Macaque_ STAMBP ( ortholog_one2one )
Mouse_ Stambp ( ortholog_one2one )
Pig_ STAMBP ( ortholog_one2one )
Rat_ Stambp ( ortholog_one2one )
Rabbit_ STAMBP ( ortholog_one2one )
OhnologsSTAMBPL1
ParalogsSTAMBPL1
TissueNA
Tissue SpecificityUbiquitously expressed. {ECO:0000269|PubMed:10383417}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001731(Rat);0.038462(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2XZE  (X-ray  1.75A  3RZU  (X-ray  2.50A  3RZV  (X-ray  1.67A  5IXF  (NMR 
DBSNP rs143739249  rs397509387  rs781694797  rs397514697  rs202100019 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:17261583, ECO:0000305|PubMed:10383417}. Membrane {ECO:0000269|PubMed:17261583};
Peripheral membrane protein {ECO:0000269|PubMed:17261583}. Cytoplasm {ECO:0000269|PubMed:17261583}. Early endosome {ECO:0000269|PubMed:15314065, ECO:0000269|PubMed:17261583}.
Mouse PG classificationNA
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