| Gene Information | |
|---|---|
| Gene Name | SLC9A9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 645 |
| Protein Names | Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000181804 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8IVB4 |
| Gene Card | SLC9A9 |
| Uniprot ID | Q8IVB4 |
| Pfam | PF00999 |
| In ASD | no |
| Allosteric Prediction | no (-0.879837539) |
| Ortholog in Animals | Alpaca_ SLC9A9 ( ortholog_one2one ) Dog_ SLC9A9 ( ortholog_one2one ) GuineaPig_ SLC9A9 ( ortholog_one2one ) Macaque_ SLC9A9 ( ortholog_one2one ) Mouse_ Slc9a9 ( ortholog_one2one ) Pig_ SLC9A9 ( ortholog_one2one ) Rat_ Slc9a9 ( ortholog_one2one ) Rabbit_ SLC9A9 ( ortholog_one2one ) |
| Ohnologs | SLC9A7, SLC9A6 |
| Paralogs | SLC9A7, SLC9A6, SLC9C1, SLC9A4, SLC9A1, SLC9A5, SLC9A3, SLC9A2, SLC9A8, SLC9C2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in all tissues tested. Expressed at highest levels in heart and skeletal muscle, followed by placenta, kidney, and liver. Expressed in the brain, in the medulla and spinal cord. {ECO:0000269|PubMed:14569117, ECO:0000269|PubMed:15522866}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16853300 rs2289491 |
| Subcellular location [CC] | Late endosome membrane {ECO:0000269|PubMed:15522866}; Multi-pass membrane protein {ECO:0000269|PubMed:15522866}. |
| Mouse PG classification | NA |
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