| Gene Information | |
|---|---|
| Gene Name | SLC9A8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 581 |
| Protein Names | Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000197818 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9Y2E8 |
| Gene Card | SLC9A8 |
| Uniprot ID | Q9Y2E8 |
| Pfam | PF00999 |
| In ASD | no |
| Allosteric Prediction | no (-0.436114694) |
| Ortholog in Animals | Alpaca_ SLC9A8 ( ortholog_one2one ) Dog_ SLC9A8 ( ortholog_one2one ) GuineaPig_ SLC9A8 ( ortholog_one2one ) Macaque_ SLC9A8 ( ortholog_one2one ) Mouse_ Slc9a8 ( ortholog_one2one ) Pig_ SLC9A8 ( ortholog_one2one ) Rat_ Slc9a8 ( ortholog_one2one ) Rabbit_ SLC9A8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC9A7, SLC9A6, SLC9C1, SLC9A4, SLC9A1, SLC9A9, SLC9A5, SLC9A3, SLC9A2, SLC9C2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Strongly expressed in skeletal muscle and kidney. {ECO:0000269|PubMed:15522866}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:15522866}; Multi-pass membrane protein {ECO:0000269|PubMed:15522866}. |
| Mouse PG classification | NA |
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