| Gene Information | |
|---|---|
| Gene Name | SLC43A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 491 |
| Protein Names | Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000134802 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NBI5 |
| Gene Card | SLC43A3 |
| Uniprot ID | Q8NBI5 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | no (-1.366107994) |
| Ortholog in Animals | Alpaca_ SLC43A3 ( ortholog_one2one ) Dog_ SLC43A3 ( ortholog_one2one ) Macaque_ SLC43A3 ( ortholog_one2one ) Mouse_ Slc43a3 ( ortholog_one2one ) Pig_ SLC43A3 ( ortholog_one2one ) Rat_ Slc43a3 ( ortholog_one2one ) Rabbit_ SLC43A3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1). {ECO:0000269|PubMed:26455426, ECO:0000269|Ref.1}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34799622 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:26455426}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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