| Gene Information | |
|---|---|
| Gene Name | UNQ584/PRO1154 |
| Organism | Homo sapiens (Human) |
| Gene Length | 941 |
| Protein Names | Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NZ08 |
| Gene Card | ERAP1 |
| Uniprot ID | Q9NZ08 |
| Pfam | PF11838; PF01433; PF17900 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2YD0 (X-ray 2.70A ) 3MDJ (X-ray 2.95A ) 3QNF (X-ray 3.00A ) 3RJO (X-ray 2.30A ) 5J5E (X-ray 2.80A ) 6M8P (X-ray 3.31A ) 6MGQ (X-ray 2.92A ) 6Q4R (X-ray 1.60A ) 6RQX (X-ray 1.68A ) 6RYF (X-ray 1.72A ) 6T6R (X-ray 1.67A ) 7MWB (X-ray 3.20A ) 7MWC (X-ray 3.00A ) 7Z28 (X-ray 1.55A ) |
| DBSNP | rs3734016 rs26653 rs26618 rs27895 rs2287987 rs30187 rs6863093 rs10050860 rs17482078 rs27044 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305|PubMed:15908954}; Single-pass type II membrane protein {ECO:0000305|PubMed:15908954}. |
| Mouse PG classification | NA |
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